Hawthorn Berries And Lozartan

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Hawthorn Berries And Lozartan

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Hawthorn is the oldest medicinal plant in Europe. Its flowers, leaves and berries are considered very valuable, especially as a cure for heart disease. This plant can provide additional benefits to people with high cholesterol, diabetes and anxiety. Read on to find out more about Hawthorn and how to use it safely.

Hawthorns (Crataegus spp.) are thorny trees or shrubs with white flowers and red berries. Although the name “Hawthorn” originally referred to the common hawthorn (C. monogyna), it is now used for the entire genus and even for its relatives (Rhaphiolepis) [1+].

Hawthorns are native to Europe, North America and Asia. They belong to the same family of roses and many edible fruits such as apples, pears, plums and cherries (Rosaceae) [2].

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Hawthorn is the oldest known medicinal plant in Europe and its use was first documented 2,000 years ago. In traditional European and American medicine, it is used [3+, 4+, 2]:

The German Commission approved the use of hawthorn for mild heart failure in the 1980s. Hawthorn extracts are mainly obtained from the common and English (C. laevigata) hawthorn, their hybrids, and other European species [3+].

The ingredients used in Europe and America are found in berries, leaves and flowers. Berries must contain at least 1% procyanidin, while leaves and flowers need a minimum of 1.5% flavonoid [1+].

In China, only the berries and leaves are used. There are no requirements for berries, but the leaves must contain at least 7% flavonoids and 0.05% hyperoside [1+].

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The berries are also eaten fresh or used to make wine, jam and candies in both China and Europe [1+].

Flavonoids are concentrated in flowers. Berries are also rich in them, but the ripe ones are very few. The leaves are high in vitexin and oligomeric proanthocyanidins [10, 11+].

Although not approved by the FDA, hawthorn extract is available commercially as a supplement, especially for heart disease. Regulations set production standards but do not guarantee that they are safe or effective. Talk to your doctor before using hawthorn to avoid unexpected interactions.

Although conventional treatments improve symptoms and reduce the death rate, people with heart disease often have a poor quality of life. Hawthorn can be combined with drugs and supplements to improve heart failure [2].

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Hawthorn extract (240-1,800 mg/day), both alone and as an adjunctive treatment, improves mild heart failure according to two meta-analyses and 8 studies in people with 4k. It increased pumping power while reducing fatigue and shortness of breath [12, 13, 14, 15, 16, 17, 18, 19, 20, 21].

However, the product did not improve symptoms of heart failure in 2 studies involving about 3k people who also took conventional medicine; it only reduced the risk of sudden death. However, the sample size was not sufficient, as most of the included people had moderate to severe heart failure [22, 23].

Homeopathic hawthorn remedies are also used, although they may not contain active ingredients. In another test on more than 200 people, homeopathic hawthorn (10-20 drops, 3x/day) was as effective as conventional drugs. However, the study had many flaws (lack of randomization and blinding, assessment of commitment rates, and short follow-up) [24+].

Arterial blood can constrict in the legs in people with heart disease, leading to swelling. In 2 studies on more than 1k people with heart disease, hawthorn extract (900 mg/day) reduced leg swelling [14, 15].

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In mice and cells, the extract reduces blood flow from vessels by strengthening their inner lining [25, 26].

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High blood pressure is the most important risk factor for heart disease. Hawthorn extract (500-1, 200 mg/day) lowered blood pressure in 4 clinical trials in about 300 people [27+, 28, 29, 30, 18].

The product also lowers blood pressure in rats and relaxes arteries in tissue studies [31, 32, 33, 34, 35].

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Orthostatic hypotension (literally, “low blood pressure standing up”) is a condition that causes a sudden drop in blood pressure after standing up quickly.

In Germany, a combination of hawthorn berries and camphor is often used to raise blood pressure in people prone to orthostatic hypotension. This remedy (5-80 drops/day) worked in 6 clinical trials on more than 500 people, but its rapid action suggests that camphor is responsible for the effect [36, 37, 38, 39 , 40, 41].

Hawthorn is a long-tested natural remedy for mild heart problems, including heart failure and high blood pressure. It can be safely added to common drugs and interventions. However, it may not work for a short period of time or on its own in people with serious heart conditions.

However, be aware that hawthorn is not approved by the FDA for heart disease. You can try this herb if you and your doctor decide that it may be suitable for improving your arthritis. Remember that taking hawthorn should not be done outside of what your doctor recommends or prescribes.

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Poor blood flow to the heart and oxygen supply can be caused by a blockage in the blood vessels that supply the heart (coronary arteries). This eventually causes chest pain or angina [42+].

A buildup of cholesterol in the arteries is a very common cause of chest pain. In a clinical trial on 80 people with chest pain, hawthorn extract (240 mg, 2x/day) combined with exercise prevented the occlusion of blood vessels [43].

Hawthorn tablets alleviated chest pain in a Chinese clinical trial on 46 people. However, we were unable to find detailed study data to analyze it [44+].

In animals and cells, the hawthorn extract prevented high blood cholesterol, inflammation, LDL damage by free radicals, and thickening of the artery wall—all of which increase the risk of stroke. [45, 46, 47, 48, 49, 50].

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Nerves can also be blocked by blood clots. Although the hawthorn extract prevented platelets from aggregating in test-tube animals, a higher dose (2,400 mg/day) was ineffective in a 16-person trial [51, 52, 53, 54, 55+].

Sealing operations can damage the inner walls, making the ship lighter. In rats, hawthorn extract prevented this unwanted effect [56].

In a trial of 49 people, hawthorn extract (400 mg, 3x / day) reduced blood cholesterol, both free and bound to LDL. Similarly, a combination containing 129 mg hawthorn and other herbs (Asiatic water plant, corn silk, Chinese knotweed, lingzhi mushroom and mulberry) reduced LDL cholesterol in a human trial. 42 (4 capsules, 2x/day) [57, 58] .

Overall, the available evidence is insufficient to say that hawthorn lowers blood cholesterol. Further clinical studies are needed to confirm these preliminary results.

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In a clinical trial on more than 250 people with anxiety disorders, a formulation containing hawthorn, California poppy, and magnesium (2 pills, 2x/day) reduced anxiety. Similarly, a combination with hawthorn and other herbs (purple passionflower, valerian, black horehound, guarana, and kola nut) was successful in a trial of about 200 people (2 tablets, 3x/day ) [63, 64].

However, many of the natural chemicals used in the types mentioned above have anti-anxiety properties. It is difficult to say whether hawthorn contributed to the benefits.

Chronic stress and depression are closely linked. Different compounds containing Chinese hawthorn but not exotic reduced stress in stressed mice [67, 68, 69, 70].

Two clinical studies using hawthorn as part of herbal formulations and a few animal studies cannot be considered as sufficient evidence. Further clinical trials testing hawthorn alone should be conducted to determine whether it has anti-anxiety effects in humans.

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A traditional Chinese medicine containing hawthorn, goji berry, safflower, kombu, and mulberry extracts (Menoprogren, 4x/day) reduced menopausal symptoms such as hot flashes, and mood swings in a trial of 83 women. It also improved low levels of sex hormones (estradiol and progesterone) [71].

Menoprogren also inhibits sex hormone fluctuations in menopausal rats by protecting their ovarian follicles [72, 73, 74, 75].

In a clinical trial on 20 women, a combination of hawthorn and ginseng extracts on the eyelids reduced wrinkles while increasing skin elasticity, moisture and radiance [76].

UV rays accelerate the aging of the skin by reducing its collagen. In mice and skin cells exposed to UV, hawthorn extract increased collagen

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