Sinatra Md, Hawthorn Berries, Insulin Resistance – The Heart of the Matter “Cardio-Gems” for Heart Cell Repair and Restoration with Dr. Stephen Sinatra -300×169-copy.png Naturopath News & Reviews https:///wp-content/uploads/2016/01/17588825_ml.jpg 200px 200px
Thank you, Dr. Sinatra, for taking time out of your busy schedule to share some clinical pearls from your vast repertoire of functionally-integrated expertise in cardiology with the naturopathic community. Many of our ND readers follow your advice and would appreciate any exam room insight you can share. I would like to focus our brief interview on several important clinical challenges facing cardiology that NDs often face.
Sinatra Md, Hawthorn Berries, Insulin Resistance
Dr. Sinatra: After graduating from Albany Medical School [Albany, New York] in 1972, I did a 3-year medical residency, followed by a 2-year fellowship in cardiovascular disease. I spent 10 years getting a certificate in bioenergetic psychotherapy, because I needed a more in-depth experience to see how character analysis affects the mind-body interaction of illness. At this time, I realized that I needed more training in nutritional medicine and took the CNS [Certified Nutrition Specialist] certification exam offered by the American College of Nutrition. Exam preparation includes 2 years of intensive study in nutritional and metabolic considerations of health and wellness. I received a certificate in antiaging medicine at the same time. In 2005, I wrote the first version
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[Laguna Beach, CA: Basic Health Publications, Inc.; 2005], which studies energy substrates and the concept of the heart, because heart failure is literally an “energy-starved heart”. It was how adenosine triphosphate (ATP) participates in metabolic pathways that led me to look deeper into the concepts of energy medicine. The concept of metabolic cardiology introduced me to vibrational medicine, an extension of the powerful concepts of disease. Since every living thing has a frequency, vibrational medicine is truly the future of medicine and currently where my passion lies. I lecture throughout the United States on vibration medicine, as well as metabolic cardiology, and include grounding and earthing in these talks. I discuss all of these ideas in my monthly newsletter,
[www.drsinatra.com], which I have been doing for the past 15 years. My latest web site, www.heartmdinstitute.com, is an informational non-commercial site dedicated to educating and empowering people to overcome heart disease.
Let’s start with the laboratory evaluation. What are the best initial screening tests to order for a new patient with suspected risk as part of a cardiovascular workup?
[glycated hemoglobin], and triglycerides as indicators of impending inflammation. Also, I look at homocysteine, LP(A) [lipoprotein(A)] (the real cholesterol story), fibrinogen, ferritin, and C-reactive protein as markers of inflammation. Whenever I do a cholesterol test, it must be fractionated to assess the inactive HDL [high-density lipoprotein], as well as the amount and number of small-particle inflammatory LDL [low-density lipoprotein]. I VAP [vertical auto profile; Atherotech Diagnostic Lab, Birmingham, AL] or LPP [lipoprotein particle profile; SpectraCell Laboratories, Houston, TX] profile.
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What is more important for heart attack prevention: lowering LDL cholesterol to 70 mg/dL or below or increasing cardiac cell omega-3 levels by at least 8% or more? Or both? Or are there other best options?
Dr. Sinatra: Honestly, I don’t think high LDL is a serious risk factor for heart disease, because we think the cholesterol theory is a hypothesis to begin with. LDL cholesterol may be the culprit, but it is not the culprit of cardiovascular disease. Inflammation and blood viscosity are the real culprits behind cardiovascular disease, so I would say without a doubt that omega-3 levels are very important in preventing heart attacks, because it addresses both viscosity and inflammation. In my opinion lowering LDL cholesterol to 70 or below is not smart medicine, as severe effects can affect both cognition and memory, as well as make us more susceptible to MRSA [methicillin-resistant
With hypertension, new research suggests aggressive therapy to achieve goals below 130/80 mm Hg, especially in patients with type 2 diabetes, may not improve stroke prevention and cardiovascular disease outcomes. What is your recommendation?
Dr. Sinatra: Although lowering blood pressure is desirable, markers of inflammation in type 2 diabetes should also be lowered. This is why lowering blood pressure numbers may not be the key to success. Treatment and prevention of insulin resistance and type 2 diabetes must include weight loss, reduction of excess fat, and improvement of inflammatory mediators, as well as a good walking or exercise program.
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Dr. Sinatra: I use natural alternatives to antihypertensive drugs in cases of mild hypertension and when there is renal impairment or renal insufficiency. I really like a metabolic cardiology approach with CoQ10 [coenzyme Q
], broad-spectrum carnitine, magnesium and ribose as a way to improve energy levels, while at the same time repairing cells. Many of my patients have also had significant reductions in blood pressure with this metabolic regimen. In other cases, I had to use nattokinase (50-100 mg per day), garlic (1000 mg), hawthorn.
] (1500 mg), and fish/squid oil (1–2 g per day). Adding foods to the diet—such as sardine peptides, wakame seaweed alginate, and oatmeal essential fatty acids—are also some dietary considerations that can be used to lower blood pressure. Obviously, weight loss and exercise are key ingredients.
Dr. Sinatra: To lower triglycerides, of course carbohydrate restriction and weight loss will work. I add 1 to 3 grams of essential fatty acids to the mix. For HDL, short-acting niacin is crucial to help raise HDL. Carnitine and CoQ10 have also been helpful, as well as broad-spectrum vitamin E and tocotrienols. If I’m treating small inflammatory particle LDL or LP(a) for that matter, I prefer a combination of niacin, fish oil or squid oil, nattokinase and D-tocotrienol. Remember, you want to prevent the thrombotic and inflammatory effects of small-particle LDL as well as LP(a), and this is where the “magic” of nattokinase and omega-3 essential fatty acids lies.
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We are seeing more patients with atrial fibrillation. There is almost an epidemic of these rhythm disturbances. What is the best way to “treat Pete”?
Dr. Sinatra: You’re right. Atrial fibrillation is on the rise, and my intuition tells me it’s probably related to the toxic environment we live in. In addition to pesticides, insecticides, high mercury and other metals, wireless technologies are “everywhere” that can disturb heart rate variability. For these reasons, I believe “prevention is easier than cure,” and whenever we can neutralize mitochondrial toxins or depress the autonomic nervous system, we can reduce the likelihood of atrial fibrillation. For example, recent studies – such as multiple anecdotal studies of prevention of atrial fibrillation with yoga and grounding or earthing – have demonstrated favorable outcomes of improved sympathetic tone in the heart. So when it comes to atrial fibrillation, again prevention is easier than cure. Stopping or limiting alcohol, sugars and caffeine is recommended in patients prone to atrial fibrillation. Once the patient is in atrial fibrillation, response to natural therapy is not very desirable. However, natural therapies (including metabolic cardiology), as well as toxin reduction (including EMF [electromagnetic field]), will help keep a person from atrial fibrillation if they are in sinus rhythm.
Peripheral artery disease (PAD) is also a cardiology challenge. What insights can you share about improving lower limb circulation?
Dr. Sinatra: The best insight I can give you about PAD is the use of GPLC (glycine propionyl), which not only helps remove toxic metabolites from the mitochondria, but GPLC releases nitric oxide (NO) at the same time. Such a combination offers a perfect solution to prevent spasm of small blood vessels in an ischemic situation. Two to four grams of GPLC with 100 to 200 mg of CoQ10, 200 to 400 mg of magnesium citrate or glycinate, and 5 g of ribose twice daily and especially after exercise Sinatra solution for PAD.
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Dr. Sinatra: The metabolic cardiology approach to congestive heart failure works perfectly: the sicker the patient, the more nutritional support you need. For example, in mild heart failure, you may need only 100 to 300 mg of CoQ10 but 300 to 600 mg in patients with severe cardiomyopathy or patients awaiting a heart transplant. In addition to CoQ10, 5 grams of ribose 3 times daily and 1 to 3 grams of broad-spectrum carnitine and 200 to 400 mg of broad-spectrum magnesium are extremely helpful in addressing an energy-starved heart. If this approach did not significantly improve quality of life after 4 weeks, the addition of 500 mg hawthorn berries 3 times daily and 1000 mg taurine 3 times daily also improved the suffering of these patients. Grounding and earthing improves blood viscosity, thus increasing blood flow.
Dr. Sinatra: Yes. I have seen plaque reversal in some of my patients when they included a metabolic cardiology program with at least 300 µg of vitamin K.
(menaquinone-7) on a daily basis. Pomegranate juice and green tea, as well as omega-3 fats in the diet as well as in supplement form, are certainly helpful