Sinatra Md, Insulin Resistance, Hawthorn Berries – The Heart of Things “Cardio Gems” for Heart Cell Repair and Renewal with Dr. Stephen Sinatra, MD2011-10-052017-05-05https:///wp-content/uploads/2015/09/-logo-with-web1 -300×169 -copy.png News and reviews of naturopathic doctors https:///wp-content/uploads/2016/01/17588825_ml.jpg 200px 200px
Dr. Sinatra, thank you for taking time out of your busy schedule to share some clinical pearls from your vast reservoir of functional-integrative cardiology expertise with the naturopathic community. Many of our ND readers are following your advice and would appreciate any screening room insight you would share. I would like to focus our brief interview on several important clinical challenges facing cardiology and that NDs often encounter.
Sinatra Md, Insulin Resistance, Hawthorn Berries
Dr. Sinatra: After graduating from Albany Medical School [Albany, New York] in 1972, I did a three-year medical residency and then a two-year fellowship in cardiovascular disease. I spent 10 years getting certified in bioenergetic psychotherapy because I needed a deeper experience in studying how character analysis affects mind-body interactions in illness. During this time, I realized that I needed additional training in nutritional medicine and passed the CNS [certified nutritionist] certification exam given by the American College of Nutrition. Preparation for the exam involved 2 years of intensive study on nutritional and metabolic considerations in health and wellness. Around the same time, I got certified in anti-aging medicine. In 2005, I wrote the first edition
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[Laguna Beach, CA: Basic Health Publications, Inc; 2005], which studies the concept of energy substrates and the heart, since heart failure is literally a “heart without energy”. Understanding how adenosine triphosphate (ATP) participates in metabolic pathways led me to delve deeper into the concepts of energy medicine. The concept of metabolic cardiology launched me into vibrational medicine, which is an extension of the energetic concepts of disease. Since every living thing has frequencies, vibrational medicine is truly the future of medicine and currently where my passion resides. I lecture on vibrational medicine as well as metabolic cardiology throughout the US and incorporate grounding and grounding into these discussions. I discuss all these concepts in my monthly newsletter,
[www.drsinatra.com], which I have been doing for the last 15 years. My newest website, www.heartmdinstitute.com, is an informative non-commercial site dedicated to educating and empowering people to help themselves overcome cardiovascular disease.
Let’s start with the laboratory assessment. What are the best initial screening tests for a new patient with suspected risks as part of a cardiovascular workup?
[glycated hemoglobin] and triglycerides as indicators of impending inflammation. Additionally, I look at homocysteine, Lp(a) [lipoprotein(a)] (the real cholesterol story), fibrinogen, ferritin, and C-reactive protein as markers of inflammation. Whenever I check cholesterol, it has to be fractionated to assess dysfunctional HDL [high-density lipoprotein] as well as determine the amount and number of small inflammatory LDL [low-density lipoprotein] particles. I use VAP [Vertical Automatic Profile; Atherotech Diagnostics Lab, Birmingham, AL] or LPP [Lipoprotein Particle Profile; SpectraCell Laboratories, Houston, TX] profiles.
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What is more important for heart attack prevention: lowering LDL cholesterol to 70 mg/dL or lower or increasing heart cell omega-3 levels to at least 8% or higher? Or both? Or is there another best option?
Dr. Sinatra: Honestly, I don’t think high LDL is a serious risk factor for heart disease, since we remember that the cholesterol theory is a hypothesis. LDL cholesterol may be at the scene of the crime, but it is not the culprit in cardiovascular disease. Inflammation and blood viscosity are the real culprits in cardiovascular disease, so I would say without a doubt that omega-3 levels are much more important in heart attack prevention, since they work on both viscosity and inflammation. Getting your LDL cholesterol down to 70 or lower is not smart medicine in my opinion, as serious consequences can result in both cognition and memory, as well as making us more susceptible to MRSA [methicillin-resistant
In hypertension, new studies suggest that aggressive therapy to achieve goals below 130/80 mm Hg does not necessarily improve outcomes in the prevention of stroke and cardiovascular disease, especially in patients with type 2 diabetes. What are your recommendations?
Dr. Sinatra: Although it is desirable to lower blood pressure, in type 2 diabetes the inflammation index must also be lower. Therefore, lowering blood pressure may not be the key to success. Weight reduction, loss of excess adipose tissue, and improvement of inflammatory mediators, as well as a good walking or exercise program, must be introduced in the treatment and prevention of insulin resistance and type 2 diabetes.
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Dr. Sinatra: I use natural alternatives to antihypertensives in situations of mild hypertension and when there is no kidney damage or renal insufficiency. I really like the metabolic cardiology approach, including CoQ10 [coenzyme Q
], broad-spectrum carnitine, magnesium and ribose as a way of improving energy substrates, while at the same time restoring cells. Many of my patients on this metabolic approach have also had significant reductions in blood pressure. In other cases, I had to use nattokinase (50-100 mg daily), garlic (1000 mg), hawthorn [
] (1500 mg) and fish/squid oil (1-2 g per day). Adding foods to the diet – such as sardine peptides, wakame alginates and oatmeal essential fatty acids – are also some of the nutritional reasons that can be used to lower blood pressure. Obviously weight loss and exercise are key ingredients.
Dr. Sinatra: To lower triglycerides, carbohydrate restriction and weight loss will certainly work. I also add 1 to 3 g of essential fatty acids to the mixture. For HDL, short-acting niacin is key to raising HDL. Carnitine and CoQ10 were also helpful, as were broad-spectrum vitamin E and tocotrienols. If I’m treating small inflammatory LDL particles or LP(s), for that matter, I like a combination of niacin, fish oil or squid oil, nattokinase, and d-tocotrienol. Remember, you want to counteract the thrombotic and inflammatory effects of small-particle LDL as well as LP(s), and that’s where nattokinase and omega-3 essential fatty acids do their “magic.”
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We are seeing many more patients with atrial fibrillation. There is almost an epidemic of this dysrhythmia. What is the best way to “cure the beat?”
Dr. Sinatra: You’re right. Atrial fibrillation is on the rise, and my intuition tells me it’s probably related to the toxic environment we live in. In addition to insecticides, pesticides, high levels of mercury and other metals, wireless technologies are “everywhere” that can disrupt heart rate variability. For these reasons, I believe that “prevention is better than cure,” and whenever we can neutralize mitochondrial toxins or weaken the autonomic nervous system, we can reduce the likelihood of atrial fibrillation. For example, recent research—such as yoga and numerous anecdotal cases of prevention of atrial fibrillation through grounding or grounding—has shown favorable outcomes of improved sympathetic tone on the heart. So, when it comes to atrial fibrillation, it is again easier to prevent than to treat. In patients who are prone to atrial fibrillation, it is recommended to stop or limit the consumption of alcohol, sugar and caffeine. When a patient is in atrial fibrillation, the response to natural therapies is not very desirable. However, natural therapies (including metabolic cardiology), as well as toxin reduction (including EMF [electromagnetic field]), will help keep a person out of atrial fibrillation once they are in sinus rhythm.
Peripheral artery disease (PAD) is also a cardiology challenge. What insight can you share about improving lower limb circulation?
Dr. Sinatra: The best insight I can give you about PAD is the use of GPLC (glycine propionyl), which not only helps remove toxic metabolites from the mitochondria, but GPLC also releases nitric oxide (NO) at the same time. Such a combination offers a perfect solution for preventing spasm of smaller blood vessels in an ischemic situation. Two to four grams of GPLC combined with 100 to 200 mg of CoQ10, 200 to 400 mg of magnesium citrate or glycinate, and 5 g of ribose twice daily, especially after exercise, is Sinatra’s solution for PAD.
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Dr. Sinatra: The metabolic cardiology approach to congestive heart failure absolutely works: the sicker the patient, the more nutritional support you need. For example, in mild heart failure you may only need 100 to 300 mg of CoQ10, but 300 to 600 mg in patients with severe cardiomyopathy or in patients awaiting a heart transplant. Along with CoQ10, 5 g of ribose 3 times a day and 1 to 3 g of broad-spectrum carnitine and 200 to 400 mg of broad-spectrum magnesium are extremely helpful in treating an energy-deficient heart. If this approach did not offer a significant improvement in quality of life after 4 weeks, supplementation with 500 mg hawthorn berries 3 times daily and 1000 mg taurine 3 times daily also improved the suffering of these patients. Grounding and grounding also helped by improving the viscosity of the blood, thereby improving blood flow.
Dr. Sinatra: Yes. I have seen plaque reversal in some of my patients when they started a metabolic cardiology program with at least 300 µg of vitamin K
(menaquinone-7) on a daily basis. Pomegranate juice and green tea, as well as omega-3 fats in the diet, as well as supplementation, are certainly helpful